Epidemiology of HIV/AIDS among students in Shandong Province from 2010 to 2019 / 中国学校卫生

Objective@#To analyze the epidemiological characteristics of HIV/AIDS infected students in Shandong Province, to provide a basis for the prevention and control of AIDS transmission in the student population.@*Methods@#All 863 HIV/AIDS students cases during 2010-2019 were collected in Shandong Province. Epidemiological characteristics was described and the trends in the 10 years since 2010 was analyzed.@*Results@#These 863 HIV/AIDS students were mainly transmitted through homosexual sex (763 cases, 88.41%), and the samples were mainly from voluntary consultation testing (433 cases, 50.17%). From 2010 to 2019, the proportion of student cases in the total number of cases showed an increasing trend ( χ 2 trend =30.21, P <0.01). Among them, the proportion of homosexual transmission cases increased year by year ( χ 2 trend =6.35, P =0.01), the proportion of cases aged 18-22 years increased year by year ( χ 2 trend =6.10, P =0.01), the proportion of cases with college degree or above increased year by year ( χ 2 trend =4.26, P =0.04). At present, voluntary consultation testing were the main source.There was no significant difference between the years of sample sources ( χ 2 trend =2.97, P =0.09).@*Conclusion@#The report number of students in Shandong Province are on the rise in recent years, especially those infected by same sex transmission, mainly with high education background, which calls for targeted strategies and intervention measures.

Accuracy of dexmedetomidine titration in diagnosis of restless legs syndrome / 中华麻醉学杂志

The medical records of patients of both sexes with sleep disorders treated with multimodal sleep therapy for which patient controlled sleep with dexmedetomidine was the main method, aged≥18 yr, with body mass index of 18-30 kg/m 2, from February 2019 to January 2021, were collected.Dexmedetomidine 60 ml/h (4 μg/ml) was intravenously infused until non-rapid eye movement (NREM) Ⅲ phase was reached or the consumption of dexmedetomidine reached 1 μg/kg.Whether dexmedetomidine induced restless legs syndrome (RLS) was judged according to the Chinese guidelines for the diagnosis and treatment of restless legs syndrome (2021 edition). When the titration was stopped and on the next day after emergence from anesthesia, clinical diagnosis was performed according to Chinese guidelines for the diagnosis and treatment of restless legs syndrome (2021 edition) to determine whether RLS was combined or not.Kappa consistency analysis was used to assess the consistency between dexmedetomidine titration and the Chinese guidelines for the diagnosis and treatment of restless legs syndrome (2021 Edition) in diagnosis of RLS.The sensitivity and specificity of diagnosis of RLS by dexmedetomidine titration were calculated.A total of 39 patients were included and 8 patients had RLS symptoms which were judged accroding to dexmedetomidine titration.The results of Kappa consistency test showed that there was a strong consistency between dexmedetomidine titration and Chinese guidelines for the diagnosis and treatment of restless legs syndrome (2021 edition) (Kappa value 1.0, P<0.01). The sensitivity and specificity of dexmedetomidine titration in judging RLS were 100%.In conclusion, dexmedetomidine titration can accurately judge RLS.

Effect of psychosocial nursing intervention on analgesic efficacy of labour analgesia in parturients / 中华麻醉学杂志

Objective To evaluate the effect of psychosocial nursing intervention on the analgesic efficacy of labour analgesia in parturients.Methods A total of 160 parturients,aged 18-35 yr,with a singleton fetus in vertex presentation at 38-41 week gestation,who required labor analgesia voluntarily,were divided into 2 groups (n =80 each) using a random number table:control group (group C) and psychosocial nursing intervention group (group Ⅰ).The epidural catheter was placed at L2.3 interspace when the cervical dilation was 3 cm,and 0.1％ ropivacaine 12 ml was injected.And then patient-controlled epidural analgesia (PCEA) was performed.The solution for PCEA contained 0.1％ ropivacaine and hydromorphone hydrochlorid 2.5 μg/ml (diluted to 160 ml in 0.9％ normal saline).The catheter was connected to a PCEA pump programmed to deliver 6 ml with a lockout interval of 12 min,background infusion at 0.1 ml/h and limit dose of 30 ml/h.After the initial administration of ropivacaine,parturients were only informed of the usages and notice items of the PCEA pump in group C,and in addition psychological nursing intervention was carried out,and the peak effect of drugs and principle of PCEA pump were also introduced in group Ⅰ.The intensity of pain was assessed using visual analogue scale score before labour analgesia and at 15,30,60,120,180 and 240 min after labour analgesia.The development of adverse reactions such as lower extremity numbness,motor nerve block,nausea and vomiting,pruritus,urinary retention and hypotension after labour analgesia was recorded.Parturient's satisfaction with labour analgesia was evaluated at 24 h after the end of delivery,and the rate of satisfactory analgesia was calculated.Results Compared with group C,visual analogue scale scores were significantly decreased at 60,120,180 and 240 min after labour analgesia,and the rate of satisfactory analgesia was increased in group Ⅰ (P＜0.05).One patient developed motor nerve block at 30 min after labour analgesia in group C,and no patient developed motor nerve block after labour analgesia in group Ⅰ.No adverse reactions such as lower extremity numbness,nausea and vomiting,pruritus,urinary retention or hypotension were found in the two groups.Conclusion Psychosocial nursing intervention can raise the analgesic efficacy of labour analgesia in parturients.

Theoretical study on thirteen or fourteen incompatible medicaments and opposite drug properties of Tujia ethnic medical science / 中国中药杂志

Tujia ethnic medical science is an important sub-discipline of China's ethnic medicine system, which has rooted in major Tujia ethnic area such as Hunan, Hubei, Guizhou and Chongqing. It has its own theory, medication characteristic and experi-ence towards ethnic drugs. Particularly, in medication incompatibility, it has formed the principle of thirteen or fourteen incompatible medicament of traditional Tujia ethnic drugs, which play a certain role in guiding the usage and compatibility of tens of thousands of herbs. Focusing on the incompatibility that is abided by Tujia medical workers, the essay makes a textual study on the origin of herbs and conducts a preliminary study on the theoretical basis of thirteen or fourteen incompatible medicaments in terms of four properties of drugs and toxic and side-effect by reference to the records on nature and flavor and effectiveness, with a view of providing a preference to improve the incompatibility theory of traditional Chinese medicines and new ideas to further studies on the development and application of traditional ethnic drugs.